1S8A

H98Q Mutant of Methylglyoxal Synthase from E. coli complexed with Phosphoglycolic Acid

Summary for 1S8A

Related1S89
DescriptorMethylglyoxal synthase, 2-PHOSPHOGLYCOLIC ACID (3 entities in total)
Functional Keywordsglycolytic bypass, methylglyoxal, lyase
Biological sourceEscherichia coli
Cellular locationCytoplasm P0A731
Total number of polymer chains6
Total molecular weight102501.34
Authors
Harrison, D.H.,Marks, G.T.,Susler, M. (deposition date: 2004-01-31, release date: 2004-03-30, Last modification date: 2011-07-13)
Primary citation
Marks, G.T.,Susler, M.,Harrison, D.H.
Mutagenic studies on histidine 98 of methylglyoxal synthase: effects on mechanism and conformational change.
Biochemistry, 43:3802-3813, 2004
PubMed: 15049687 (PDB entries with the same primary citation)
DOI: 10.1021/bi035838o
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.2 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.2207 0.7% 3.1% 1.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
171916
PDB entries from 2020-12-02