1S7G

Structural Basis for the Mechanism and Regulation of Sir2 Enzymes

Summary for 1S7G

Entry DOI	10.2210/pdb1s7g/pdb
Descriptor	NAD-dependent deacetylase 2, ADENOSINE-5-DIPHOSPHORIBOSE, ZINC ION, ... (11 entities in total)
Functional Keywords	enzyme, sirtuin, sir2, nad+, adp-ribose, transcription
Biological source	Archaeoglobus fulgidus
Cellular location	Cytoplasm (Probable): O30124
Total number of polymer chains	5
Total formula weight	148485.81
Authors	Avalos, J.L.,Boeke, J.D.,Wolberger, C. (deposition date: 2004-01-29, release date: 2004-03-23, Last modification date: 2023-08-23)
Primary citation	Avalos, J.L.,Boeke, J.D.,Wolberger, C. Structural basis for the mechanism and regulation of sir2 enzymes Mol.Cell, 13:639-648, 2004 Cited by PubMed: 15023335 DOI: 10.1016/S1097-2765(04)00082-6 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation