1S7G
Structural Basis for the Mechanism and Regulation of Sir2 Enzymes
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D, E | NAD-dependent deacetylase 2 | polymer | 253 | 28537.0 | 5 | UniProt (O30124) Pfam (PF02146) In PDB | Archaeoglobus fulgidus | Regulatory protein SIR2 homolog 2, SIR2-Af2 |
2 | A, D, E, B, C | ZINC ION | non-polymer | 65.4 | 9 | Chemie (ZN) | |||
3 | C, A, D, B | SULFATE ION | non-polymer | 96.1 | 12 | Chemie (SO4) | |||
4 | C, A, B | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 3 | Chemie (NAD) | |||
5 | A | PENTAETHYLENE GLYCOL | non-polymer | 238.3 | 1 | Chemie (1PE) | |||
6 | A, B | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
7 | B | NONAETHYLENE GLYCOL | non-polymer | 414.5 | 1 | Chemie (2PE) | |||
8 | C | HEXAETHYLENE GLYCOL | non-polymer | 282.3 | 1 | Chemie (P6G) | |||
9 | C, D | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 2 | Chemie (PG4) | |||
10 | E | ADENOSINE-5-DIPHOSPHORIBOSE | non-polymer | 559.3 | 1 | Chemie (APR) | |||
11 | water | water | 18.0 | 313 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 5 |
Total formula weight | 142685.0 | |
Non-Polymers* | Number of molecules | 33 |
Total formula weight | 5800.8 | |
All* | Total formula weight | 148485.8 |