1S7G
Structural Basis for the Mechanism and Regulation of Sir2 Enzymes
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E (A, B, C, D, E) | NAD-dependent deacetylase 2 | polymer | 253 | 28537.0 | 5 | UniProt (O30124) Pfam (PF02146) | Archaeoglobus fulgidus | Regulatory protein SIR2 homolog 2, SIR2-Af2 |
| 2 | F, FA, G, GA, KA... (A, D, E, B, C) | ZINC ION | non-polymer | 65.4 | 9 | Chemie (ZN) | |||
| 3 | AA, BA, H, HA, I... (C, A, D, B) | SULFATE ION | non-polymer | 96.1 | 12 | Chemie (SO4) | |||
| 4 | CA, L, U (C, A, B) | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 3 | Chemie (NAD) | |||
| 5 | M (A) | PENTAETHYLENE GLYCOL | non-polymer | 238.3 | 1 | Chemie (1PE) | |||
| 6 | N, W, X (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
| 7 | V (B) | NONAETHYLENE GLYCOL | non-polymer | 414.5 | 1 | Chemie (2PE) | |||
| 8 | DA (C) | HEXAETHYLENE GLYCOL | non-polymer | 282.3 | 1 | Chemie (P6G) | |||
| 9 | EA, JA (C, D) | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 2 | Chemie (PG4) | |||
| 10 | LA (E) | ADENOSINE-5-DIPHOSPHORIBOSE | non-polymer | 559.3 | 1 | Chemie (APR) | |||
| 11 | MA, NA, OA, PA, QA (A, B, C, D, E) | water | water | 18.0 | 313 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 142685.0 | |
| Non-Polymers* | Number of molecules | 33 |
| Total formula weight | 5800.8 | |
| All* | Total formula weight | 148485.8 |
