1RWE
Enhancing the activity of insulin at receptor edge: crystal structure and photo-cross-linking of A8 analogues
Summary for 1RWE
Entry DOI | 10.2210/pdb1rwe/pdb |
Related | 1MPJ |
Descriptor | insulin, Insulin, ZINC ION, ... (6 entities in total) |
Functional Keywords | a8-histidine human insulin, insulin receptor, hormone-growth factor complex, hormone/growth factor |
Cellular location | Secreted: P01308 P01308 |
Total number of polymer chains | 4 |
Total formula weight | 12005.22 |
Authors | Wan, Z.,Xu, B.,Chu, Y.C.,Li, B.,Nakagawa, S.H.,Qu, Y.,Hu, S.Q.,Katsoyannis, P.G.,Weiss, M.A. (deposition date: 2003-12-16, release date: 2005-02-15, Last modification date: 2023-08-23) |
Primary citation | Wan, Z.,Xu, B.,Huang, K.,Chu, Y.C.,Li, B.,Nakagawa, S.H.,Qu, Y.,Hu, S.Q.,Katsoyannis, P.G.,Weiss, M.A. Enhancing the activity of insulin at the receptor interface: crystal structure and photo-cross-linking of A8 analogues. Biochemistry, 43:16119-16133, 2004 Cited by PubMed: 15610006DOI: 10.1021/bi048223f PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
Download full validation report