1RU2
CRYSTAL STRUCTURE OF A TERNARY COMPLEX OF E.COLI HPPK(V83G/DEL84-89) WITH MGAMPCPP AND 6-HYDROXYMETHYLPTERIN AT 1.48 ANGSTROM RESOLUTION (ORTHORHOMBIC FORM)
Summary for 1RU2
Entry DOI | 10.2210/pdb1ru2/pdb |
Related | 1CBK 1DY3 1EQ0 1EQM 1EX8 1F9H 1F9Y 1G4C 1HKA 1HQ2 1HQ9 1IM6 1KBR 1Q0N 1RAO 1RB0 1RTZ 1RU1 |
Descriptor | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase, MAGNESIUM ION, CHLORIDE ION, ... (6 entities in total) |
Functional Keywords | pyrophosphokinase, pyrophosphoryl transfer, folate, hppk, 6-hydroxymethylpterin, 6-hydroxymethyl-7, 8-dihydropterin, antimicrobial agent, drug design, deletion mutant, transferase |
Biological source | Escherichia coli |
Total number of polymer chains | 1 |
Total formula weight | 17876.92 |
Authors | Blaszczyk, J.,Ji, X. (deposition date: 2003-12-10, release date: 2004-02-24, Last modification date: 2023-08-30) |
Primary citation | Blaszczyk, J.,Li, Y.,Wu, Y.,Shi, G.,Ji, X.,Yan, H. Essential Roles of a Dynamic Loop in the Catalysis of 6-Hydroxymethyl-7,8-dihydropterin Pyrophosphokinase. Biochemistry, 43:1469-1477, 2004 Cited by PubMed: 14769023DOI: 10.1021/bi036053l PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.48 Å) |
Structure validation
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