1RJB

Crystal Structure of FLT3

Summary for 1RJB

• Entry DOI: 10.2210/pdb1rjb/pdb
• Descriptor: FL cytokine receptor (2 entities in total)
• Functional Keywords: kinase, autoinhibition, juxtamembrane domain, transferase
• Biological source: Homo sapiens (human)
• Cellular location: Membrane; Single-pass type I membrane protein: P36888
• Total number of polymer chains: 1
• Total formula weight: 39799.32

Authors

Griffith, J.,Black, J.,Faerman, C.,Swenson, L.,Wynn, M.,Lu, F.,Lippke, J.,Saxena, K. (deposition date: 2003-11-19, release date: 2004-02-03, Last modification date: 2024-02-14)

• Primary citation: Griffith, J.,Black, J.,Faerman, C.,Swenson, L.,Wynn, M.,Lu, F.,Lippke, J.,Saxena, K.; The structural basis for autoinhibition of FLT3 by the juxtamembrane domain.; Mol.Cell, 13:169-178, 2004; PubMed: 14759363; DOI: 10.1016/S1097-2765(03)00505-7

Experimental method

X-RAY DIFFRACTION (2.1 Å)