1RAO
CRYSTAL STRUCTURE OF A TERNARY COMPLEX OF E. COLI HPPK WITH AMP AND 6-HYDROXYMETHYLPTERIN-DIPHOSPHATE AT 1.56 ANGSTROM RESOLUTION
Summary for 1RAO
Entry DOI | 10.2210/pdb1rao/pdb |
Related | 1CBK 1DY3 1EQ0 1EQM 1EX8 1F9H 1F9Y 1G4C 1HKA 1HQ2 1IM6 1KBR 1Q0N 1RB0 |
Descriptor | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase, ADENOSINE MONOPHOSPHATE, 6-HYDROXYMETHYLPTERIN-DIPHOSPHATE, ... (4 entities in total) |
Functional Keywords | pyrophosphokinase, pyrophosphoryl transfer, catalytic mechanism, folate, hppk, pterin, 6-hydroxymethyl-7, 8-dihydropterin, 6-hydroxymethylpterin, ternary complex, substrate specificity, product release, antimicrobial agent, drug design, transferase |
Biological source | Escherichia coli |
Total number of polymer chains | 1 |
Total formula weight | 18666.88 |
Authors | Blaszczyk, J.,Ji, X. (deposition date: 2003-10-31, release date: 2004-11-09, Last modification date: 2023-08-30) |
Primary citation | Blaszczyk, J.,Shi, G.,Li, Y.,Yan, H.,Ji, X. Reaction trajectory of pyrophosphoryl transfer catalyzed by 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase. Structure, 12:467-475, 2004 Cited by PubMed: 15016362DOI: 10.1016/j.str.2004.02.003 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.56 Å) |
Structure validation
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