1RAJ

Poliovirus Polymerase with a 68 residue N-terminal truncation

1RAJ の概要

• エントリーDOI: 10.2210/pdb1raj/pdb
• 関連するPDBエントリー: 1RA6 1RA7 1RDR 1TQL
• 分子名称: Genome polyprotein (2 entities in total)
• 機能のキーワード: nucleotidyltransferase, poliovirus, polio, 3d, rna-dependent, polymerase, transferase
• 由来する生物種: Human poliovirus 1
• 細胞内の位置: Capsid protein VP0: Virion. Capsid protein VP4: Virion. Capsid protein VP2: Virion. Capsid protein VP3: Virion. Capsid protein VP1: Virion. Protein 2B: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . Protein 2C: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . Protein 3A: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . Protein 3AB: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . Viral protein genome-linked: Virion. Protease 3C: Host cytoplasm. Protein 3CD: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . RNA-directed RNA polymerase: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side : P03300
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 44793.12

構造登録者

Thompson, A.A.,Peersen, O.B. (登録日: 2003-10-31, 公開日: 2004-08-17, 最終更新日: 2023-08-23)

• 主引用文献: Thompson, A.A.,Peersen, O.B.; Structural basis for proteolysis-dependent activation of the poliovirus RNA-dependent RNA polymerase.; Embo J., 23:3462-3471, 2004; PubMed: 15306852; DOI: 10.1038/sj.emboj.7600357

実験手法

X-RAY DIFFRACTION (2.5 Å)