Crystal Structure of Fosfomycin Resistance Protein FosX from Mesorhizobium Loti

Summary for 1R9C

Descriptorglutathione transferase, MANGANESE (II) ION (3 entities in total)
Functional Keywordsfosfomycin resistance protein, mn binding, antibiotic resistance, transferase
Biological sourceMesorhizobium loti
Cellular locationCytoplasm (By similarity) Q98GG1
Total number of polymer chains2
Total molecular weight32520.59
Fillgrove, K.L.,Pakhomova, S.,Newcomer, M.E.,Armstrong, R.N. (deposition date: 2003-10-28, release date: 2004-02-10, Last modification date: 2011-07-13)
Primary citation
Fillgrove, K.L.,Pakhomova, S.,Newcomer, M.E.,Armstrong, R.N.
Mechanistic diversity of fosfomycin resistance in pathogenic microorganisms.
J.Am.Chem.Soc., 125:15730-15731, 2003
PubMed: 14677948 (PDB entries with the same primary citation)
DOI: 10.1021/ja039307z
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.24321.3%2.6%9.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report