1QYX
Crystal structure of human estrogenic 17beta-hydroxysteroid dehydrogenase complex with androstenedione and NADP
Summary for 1QYX
Entry DOI | 10.2210/pdb1qyx/pdb |
Related | 1IOL 1JTV 1QYV 1QYW |
Descriptor | Estradiol 17 beta-dehydrogenase 1, 4-ANDROSTENE-3-17-DIONE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... (5 entities in total) |
Functional Keywords | 17bhsd1, androstenedione, c19-steroid, nadp binding, oxidoreductase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P14061 |
Total number of polymer chains | 1 |
Total formula weight | 36009.74 |
Authors | |
Primary citation | Shi, R.,Lin, S.X. Cofactor hydrogen bonding onto the protein main chain is conserved in the short chain dehydrogenase/reductase family and contributes to nicotinamide orientation. J.Biol.Chem., 279:16778-16785, 2004 Cited by PubMed: 14966133DOI: 10.1074/jbc.M313156200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.89 Å) |
Structure validation
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