1QYX

Crystal structure of human estrogenic 17beta-hydroxysteroid dehydrogenase complex with androstenedione and NADP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Estradiol 17 beta-dehydrogenase 1	polymer	327	34887.8	1	UniProt (P14061) Pfam (PF00106)	Homo sapiens (human)	17-beta-HSD 1, Placental 17-beta-hydroxysteroid dehydrogenase, 20 alpha- hydroxysteroid dehydrogenase, 20-alpha-HSD, E2DH
2	B (A)	4-ANDROSTENE-3-17-DIONE	non-polymer		286.4	1	Chemie (ASD) PubChem (16401731) PubChem (2193) PubChem (6128) PubChem (249335) PubChem (45038166) PubChem (45157398) PubChem (45358828) PubChem (1777655) PubChem (1777653) PubChem (1777654) PubChem (51571550) PubChem (68200178) PubChem (70987809) PubChem (6432604) PubChem (86310158) PubChem (86310317) PubChem (6603719) PubChem (7059480) PubChem (7092858) PubChem (7092862) PubChem (90350327) PubChem (712379) PubChem (719687) PubChem (10636976) PubChem (11862468) PubChem (11869386) PubChem (12502775) PubChem (12502776) PubChem (118179606) PubChem (121467525) PubChem (11869385) PubChem (124306669) PubChem (12502771) PubChem (124905398) PubChem (139408315) PubChem (141834009) PubChem (142980352) PubChem (144685561) PubChem (144685562) PubChem (163076809)
3	C (A)	NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	non-polymer		743.4	1	Chemie (NAP) PubChem (5885) PubChem (46936685) PubChem (71717786) PubChem (4412) PubChem (90473931) PubChem (91972139) PubChem (145946263) PubChem (153311489) PubChem (174001641) PubChem (165382010)
4	D (A)	GLYCEROL	non-polymer		92.1	1	Chemie (GOL) PubChem (753)
5	E (A)	water	water		18.0	115	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	34887.8
Non-Polymers*	Number of molecules	3
	Total formula weight	1121.9
All*	Total formula weight	36009.7

*Water molecules are not included.