1QPV

YEAST COFILIN

1QPV の概要

• エントリーDOI: 10.2210/pdb1qpv/pdb
• 関連するPDBエントリー: 1CFY 1COF
• 分子名称: YEAST COFILIN (1 entity in total)
• 機能のキーワード: three layers:alpha/mixed beta/alpha ; cofilin fold; actin-binding protein, actin-binding protein
• 由来する生物種: Saccharomyces cerevisiae (baker's yeast)
• 細胞内の位置: Cytoplasm: Q03048
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 15919.74

構造登録者

Fedorov, A.A.,Lappalainen, P.,Fedorov, E.V.,Drubin, D.G.,Almo, S.C. (登録日: 1999-05-29, 公開日: 1999-06-08, 最終更新日: 2023-08-16)

主引用文献

Fedorov, A.A.,Lappalainen, P.,Fedorov, E.V.,Drubin, D.G.,Almo, S.C.
Structure determination of yeast cofilin.
Nat.Struct.Biol., 4:366-369, 1997

PubMed Abstract: Cofilin, a ubiquitous 15,000 M(r) protein, plays a central role in regulating cytoskeletal dynamics. Cofilin binds to actin monomers and filaments, and has a pH-dependent actin severing activity. The structure will allow for a detailed analysis of cofilin function.

PubMed: 9145106
DOI: 10.1038/nsb0597-366

実験手法

X-RAY DIFFRACTION (3 Å)