1QPV
YEAST COFILIN
Summary for 1QPV
Entry DOI | 10.2210/pdb1qpv/pdb |
Related | 1CFY 1COF |
Descriptor | YEAST COFILIN (1 entity in total) |
Functional Keywords | three layers:alpha/mixed beta/alpha ; cofilin fold; actin-binding protein, actin-binding protein |
Biological source | Saccharomyces cerevisiae (baker's yeast) |
Cellular location | Cytoplasm: Q03048 |
Total number of polymer chains | 1 |
Total formula weight | 15919.74 |
Authors | Fedorov, A.A.,Lappalainen, P.,Fedorov, E.V.,Drubin, D.G.,Almo, S.C. (deposition date: 1999-05-29, release date: 1999-06-08, Last modification date: 2023-08-16) |
Primary citation | Fedorov, A.A.,Lappalainen, P.,Fedorov, E.V.,Drubin, D.G.,Almo, S.C. Structure determination of yeast cofilin. Nat.Struct.Biol., 4:366-369, 1997 Cited by PubMed Abstract: Cofilin, a ubiquitous 15,000 M(r) protein, plays a central role in regulating cytoskeletal dynamics. Cofilin binds to actin monomers and filaments, and has a pH-dependent actin severing activity. The structure will allow for a detailed analysis of cofilin function. PubMed: 9145106DOI: 10.1038/nsb0597-366 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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