1QJ0
HUMAN INSULIN HEXAMERS WITH CHAIN B HIS MUTATED TO TYR
Summary for 1QJ0
Entry DOI | 10.2210/pdb1qj0/pdb |
Related | 1QIY 1QIZ |
Descriptor | INSULIN A CHAIN, INSULIN B CHAIN, ZINC ION, ... (5 entities in total) |
Functional Keywords | hormone, glucose metabolism, diabetes, insulin mutant |
Biological source | HOMO SAPIENS (HUMAN) More |
Cellular location | Secreted: P01308 P01308 |
Total number of polymer chains | 4 |
Total formula weight | 11851.63 |
Authors | Tang, L.,Whittingham, J.L.,Verma, C.S.,Caves, L.S.D.,Dodson, G.G. (deposition date: 1999-06-18, release date: 1999-06-22, Last modification date: 2024-05-01) |
Primary citation | Tang, L.,Whittingham, J.L.,Verma, C.S.,Caves, L.S.D.,Dodson, G.G. Structural Consequences of the B5 Histidine --> Tyrosine Mutation in Human Insulin Characterized by X-Ray Crystallography and Conformational Analysis. Biochemistry, 38:12041-, 1999 Cited by PubMed: 10508408DOI: 10.1021/BI990700K PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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