1QA7

CRYSTAL COMPLEX OF THE 3C PROTEINASE FROM HEPATITIS A VIRUS WITH ITS INHIBITOR AND IMPLICATIONS FOR THE POLYPROTEIN PROCESSING IN HAV

Summary for 1QA7

Entry DOI	10.2210/pdb1qa7/pdb
Descriptor	HAV 3C PROTEINASE, N-(iodoacetyl)-L-valyl-L-phenylalaninamide, DIMETHYL SULFOXIDE, ... (5 entities in total)
Functional Keywords	chymotrypsin-like cysteine proteinase viral protease p'-site inhibitor, hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Hepatitis A virus
Total number of polymer chains	4
Total formula weight	97209.18
Authors	Bergmann, E.M.,Cherney, M.M.,Mckendrick, J.,Vederas, J.C.,James, M.N.G. (deposition date: 1999-04-15, release date: 1999-04-20, Last modification date: 2023-08-16)
Primary citation	Bergmann, E.M.,Cherney, M.M.,Mckendrick, J.,Frormann, S.,Luo, C.,Malcolm, B.A.,Vederas, J.C.,James, M.N. Crystal structure of an inhibitor complex of the 3C proteinase from hepatitis A virus (HAV) and implications for the polyprotein processing in HAV. Virology, 265:153-163, 1999 Cited by PubMed: 10603326 DOI: 10.1006/viro.1999.9968 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation