1Q8D
The crystal structure of GDNF family co-receptor alpha 1 domain 3
Summary for 1Q8D
Entry DOI | 10.2210/pdb1q8d/pdb |
Descriptor | GDNF family receptor alpha 1, (4S)-2-METHYL-2,4-PENTANEDIOL (3 entities in total) |
Functional Keywords | all-alpha, cys-rich, hormone-growth factor receptor complex, hormone/growth factor receptor |
Biological source | Rattus norvegicus (Norway rat) |
Cellular location | Cell membrane; Lipid-anchor, GPI-anchor: Q62997 |
Total number of polymer chains | 1 |
Total formula weight | 12193.56 |
Authors | Leppanen, V.M.,Bespalov, M.M.,Runeberg-Roos, P.,Puurand, U.,Merits, A.,Saarma, M.,Goldman, A. (deposition date: 2003-08-21, release date: 2004-08-31, Last modification date: 2011-07-13) |
Primary citation | Leppanen, V.M.,Bespalov, M.M.,Runeberg-Roos, P.,Puurand, U.,Merits, A.,Saarma, M.,Goldman, A. The structure of GFRalpha1 domain 3 reveals new insights into GDNF binding and RET activation. Embo J., 23:1452-1462, 2004 Cited by PubMed: 15044950DOI: 10.1038/sj.emboj.7600174 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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