1Q5P

S156E/S166D variant of Bacillus lentus subtilisin

Summary for 1Q5P

• Entry DOI: 10.2210/pdb1q5p/pdb
• Descriptor: Serine protease, SULFATE ION, CALCIUM ION, ... (4 entities in total)
• Functional Keywords: serine protease, subtilisin, site-specific variant, altered flexibility, hydrolase
• Biological source: Bacillus lentus
• Cellular location: Secreted: P29600
• Total number of polymer chains: 1
• Total formula weight: 27117.84

Authors

Bott, R.R.,Chan, G.,Domingo, B.,Ganshaw, G.,Hsia, C.Y.,Knapp, M.,Murray, C.J. (deposition date: 2003-08-08, release date: 2003-11-11, Last modification date: 2018-04-04)

• Primary citation: Bott, R.R.,Chan, G.,Domingo, B.,Ganshaw, G.,Hsia, C.Y.,Knapp, M.,Murray, C.J.; Do enzymes change the nature of transition states? Mapping the transition state for general acid-base catalysis of a serine protease; Biochemistry, 42:10545-10553, 2003; PubMed: 12962477; DOI: 10.1021/bi034773m

Experimental method

X-RAY DIFFRACTION (1.6 Å)