1Q3G

MurA (Asp305Ala) liganded with tetrahedral reaction intermediate

1Q3G の概要

• エントリーDOI: 10.2210/pdb1q3g/pdb
• 関連するPDBエントリー: 1a2n 1ejc 1ejd 1eyn 1naw 1q36 1uae
• 分子名称: UDP-N-acetylglucosamine 1-carboxyvinyltransferase, 3'-1-CARBOXY-1-PHOSPHONOOXY-ETHOXY-URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE, 1,2-ETHANEDIOL, ... (4 entities in total)
• 機能のキーワード: inside-out alpha-beta barrel, transferase
• 由来する生物種: Enterobacter cloacae
• 細胞内の位置: Cytoplasm : P33038
• タンパク質・核酸の鎖数: 16
• 化学式量合計: 729965.79

構造登録者

Eschenburg, S.,Kabsch, W.,Healy, M.L.,Schonbrunn, E. (登録日: 2003-07-29, 公開日: 2003-12-16, 最終更新日: 2023-08-16)

• 主引用文献: Eschenburg, S.,Kabsch, W.,Healy, M.L.,Schonbrunn, E.; A New View of the Mechanisms of UDP-N-Acetylglucosamine Enolpyruvyl Transferase (MurA) and 5-Enolpyruvylshikimate-3-phosphate Synthase (AroA) Derived from X-ray Structures of Their Tetrahedral Reaction Intermediate States.; J.Biol.Chem., 278:49215-49222, 2003; PubMed: 13129913; DOI: 10.1074/jbc.M309741200

実験手法

X-RAY DIFFRACTION (2.65 Å)