1PX5

Crystal structure of the 2'-specific and double-stranded RNA-activated interferon-induced antiviral protein 2'-5'-oligoadenylate synthetase

Summary for 1PX5

Entry DOI	10.2210/pdb1px5/pdb
Descriptor	2'-5'-oligoadenylate synthetase 1, SULFATE ION (3 entities in total)
Functional Keywords	5-stranded antiparalel beta sheet, four helix bundle, transferase
Biological source	Sus scrofa (pig)
Cellular location	Mitochondrion (By similarity): Q29599
Total number of polymer chains	2
Total formula weight	81223.12
Authors	Hartmann, R.,Justesen, J.,Sarkar, S.N.,Sen, G.C.,Yee, V.C. (deposition date: 2003-07-02, release date: 2003-11-25, Last modification date: 2011-07-13)
Primary citation	Hartmann, R.,Justesen, J.,Sarkar, S.N.,Sen, G.C.,Yee, V.C. Crystal structure of the 2'-specific and double-stranded RNA-activated interferon-induced antiviral protein 2'-5'-oligoadenylate synthetase Mol.Cell, 12:1173-1185, 2003 Cited by PubMed: 14636576 DOI: 10.1016/S1097-2765(03)00433-7 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.74 Å)

Structure validation