1PVG

Crystal Structure of the ATPase region of Saccharomyces Cerevisiae topoisomerase II

Summary for 1PVG

Entry DOI	10.2210/pdb1pvg/pdb
Related	1BGW 1BJT 1Q1D
Descriptor	DNA topoisomerase II, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... (4 entities in total)
Functional Keywords	ghkl atpase domain, isomerase
Biological source	Saccharomyces cerevisiae (baker's yeast)
Cellular location	Nucleus: P06786
Total number of polymer chains	2
Total formula weight	98196.77
Authors	Classen, S.,Olland, S.,Berger, J.M. (deposition date: 2003-06-27, release date: 2003-08-26, Last modification date: 2017-10-11)
Primary citation	Classen, S.,Olland, S.,Berger, J.M. Structure of the topoisomerase II ATPase region and its mechanism of inhibition by the chemotherapeutic agent ICRF-187 Proc.Natl.Acad.Sci.USA, 100:10629-10634, 2003 Cited by PubMed: 12963818 DOI: 10.1073/pnas.1832879100 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation