1PA1
Crystal structure of the C215D mutant of protein tyrosine phosphatase 1B
Summary for 1PA1
Entry DOI | 10.2210/pdb1pa1/pdb |
Descriptor | Protein-tyrosine phosphatase, non-receptor type 1, MAGNESIUM ION, CHLORIDE ION, ... (4 entities in total) |
Functional Keywords | phosphatase, catalytic loop, active-site mutant, hydrolase |
Biological source | Homo sapiens (human) |
Cellular location | Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side: P18031 |
Total number of polymer chains | 1 |
Total formula weight | 36511.44 |
Authors | Romsicki, Y.,Scapin, G.,Beaulieu-Audy, V.,Patel, S.B.,Becker, J.W.,Kennedy, B.,Asante-Appiah, E. (deposition date: 2003-05-13, release date: 2003-08-05, Last modification date: 2023-08-16) |
Primary citation | Romsicki, Y.,Scapin, G.,Beaulieu-Audy, V.,Patel, S.,Becker, J.W.,Kennedy, B.P.,Asante-Appiah, E. Functional characterization and crystal structure of the C215D mutant of protein-tyrosine phosphatase-1B J.Biol.Chem., 278:29009-29015, 2003 Cited by PubMed: 12748196DOI: 10.1074/jbc.M303817200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
Download full validation report