1P6O
The crystal structure of yeast cytosine deaminase bound to 4(R)-hydroxyl-3,4-dihydropyrimidine at 1.14 angstroms.
Summary for 1P6O
Entry DOI | 10.2210/pdb1p6o/pdb |
Related | 1OX7 |
Descriptor | Cytosine deaminase, ZINC ION, 4-HYDROXY-3,4-DIHYDRO-1H-PYRIMIDIN-2-ONE, ... (6 entities in total) |
Functional Keywords | cytosine deaminase, hydrolase, dimer, inhibitor bound |
Biological source | Saccharomyces cerevisiae (baker's yeast) |
Total number of polymer chains | 2 |
Total formula weight | 36141.79 |
Authors | Ireton, G.C.,Black, M.E.,Stoddard, B.L. (deposition date: 2003-04-29, release date: 2003-08-19, Last modification date: 2023-08-16) |
Primary citation | Ireton, G.C.,Black, M.E.,Stoddard, B.L. The 1.14 a crystal structure of yeast Cytosine deaminase. Evolution of nucleotide salvage enzymes and implications for genetic chemotherapy. Structure, 11:961-972, 2003 Cited by PubMed: 12906827DOI: 10.1016/S0969-2126(03)00153-9 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.14 Å) |
Structure validation
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