1P5J

Crystal Structure Analysis of Human Serine Dehydratase

1P5J の概要

• エントリーDOI: 10.2210/pdb1p5j/pdb
• 分子名称: L-serine dehydratase, PYRIDOXAL-5'-PHOSPHATE (3 entities in total)
• 機能のキーワード: lyase
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 39805.80

構造登録者

Sun, L.,Liu, Y.,Rao, Z. (登録日: 2003-04-27, 公開日: 2004-06-01, 最終更新日: 2023-10-25)

主引用文献

Sun, L.,Li, X.,Dong, Y.,Yang, M.,Liu, Y.,Han, X.,Zhang, X.,Pang, H.,Rao, Z.
Crystallization and preliminary crystallographic analysis of human serine dehydratase.
Acta Crystallogr.,Sect.D, 59:2297-2299, 2003

PubMed Abstract: L-Serine dehydratase (SDH) catalyzes the pyridoxal phosphate (PLP) dependent deamination of L-serine to yield pyruvate. Recombinant human serine dehydratase was crystallized by the hanging-drop vapour-diffusion method. Crystals were grown at 291 K using (NH4)(2)SO4 as precipitant. Diffraction data were obtained to a resolution of 2.5 A from a single frozen crystal using Cu Kalpha radiation. The crystal belongs to space group I422, with unit-cell parameters a = 157.4, b = 157.4, c = 59.2 A, alpha = beta = gamma = 90 degrees. The asymmetric unit contains one molecule and has a solvent content of about 46%.

PubMed: 14646100
DOI: 10.1107/S0907444903020110
主引用文献が同じPDBエントリー

実験手法

X-RAY DIFFRACTION (2.5 Å)