1OSV

STRUCTURAL BASIS FOR BILE ACID BINDING AND ACTIVATION OF THE NUCLEAR RECEPTOR FXR

1OSV の概要

• エントリーDOI: 10.2210/pdb1osv/pdb
• 分子名称: Bile acid receptor, Nuclear receptor coactivator 2, 6-ETHYL-CHENODEOXYCHOLIC ACID, ... (4 entities in total)
• 機能のキーワード: lbd, bile acid, coactivator, nuclear receptor, dna binding protein
• 由来する生物種: Rattus norvegicus (Norway rat); 詳細
• 細胞内の位置: Nucleus (Probable): Q62735; Nucleus: Q61026
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 58937.02

構造登録者

Mi, L.Z.,Devarakonda, S.,Harp, J.M.,Han, Q.,Pellicciari, R.,Willson, T.M.,Khorasanizadeh, S.,Rastinejad, F. (登録日: 2003-03-20, 公開日: 2004-03-23, 最終更新日: 2024-02-14)

• 主引用文献: Mi, L.Z.,Devarakonda, S.,Harp, J.M.,Han, Q.,Pellicciari, R.,Willson, T.M.,Khorasanizadeh, S.,Rastinejad, F.; Structural Basis for Bile Acid Binding and Activation of the Nuclear Receptor FXR; Mol.Cell, 11:1093-1100, 2003; PubMed: 12718893; DOI: 10.1016/S1097-2765(03)00112-6

実験手法

X-RAY DIFFRACTION (2.5 Å)