1ORV
Crystal Structure of Porcine Dipeptidyl Peptidase IV (CD26)
Summary for 1ORV
Entry DOI | 10.2210/pdb1orv/pdb |
Descriptor | dipeptidyl peptidase IV, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total) |
Functional Keywords | serine protease, oxyanion hole, substrate channeling, drug design, diabetes mellitus, hydrolase |
Biological source | Sus scrofa (pig) |
Total number of polymer chains | 4 |
Total formula weight | 345563.39 |
Authors | Engel, M.,Hoffmann, T.,Wagner, L.,Wermann, M.,Heiser, U.,Kiefersauer, R.,Huber, R.,Bode, W.,Demuth, H.U.,Brandstetter, H. (deposition date: 2003-03-16, release date: 2003-05-06, Last modification date: 2020-07-29) |
Primary citation | Engel, M.,Hoffmann, T.,Wagner, L.,Wermann, M.,Heiser, U.,Kiefersauer, R.,Huber, R.,Bode, W.,Demuth, H.U.,Brandstetter, H. The Crystal Structure of Dipeptidyl Peptidase IV (CD26) Reveals its Functional Regulation and Enzymatic Mechanism Proc.Natl.Acad.Sci.USA, 100:5063-5068, 2003 Cited by PubMed: 12690074DOI: 10.1073/pnas.0230620100 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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