1OPJ
Structural basis for the auto-inhibition of c-Abl tyrosine kinase
Summary for 1OPJ
Entry DOI | 10.2210/pdb1opj/pdb |
Related | 1OPK 1OPL |
Descriptor | Proto-oncogene tyrosine-protein kinase ABL1, CHLORIDE ION, MYRISTIC ACID, ... (5 entities in total) |
Functional Keywords | transferase |
Biological source | Mus musculus (house mouse) |
Cellular location | Cytoplasm, cytoskeleton: P00520 |
Total number of polymer chains | 2 |
Total formula weight | 69001.90 |
Authors | Nagar, B.,Hantschel, O.,Young, M.A.,Scheffzek, K.,Veach, D.,Bornmann, W.,Clarkson, B.,Superti-Furga, G.,Kuriyan, J. (deposition date: 2003-03-06, release date: 2003-04-08, Last modification date: 2024-03-13) |
Primary citation | Nagar, B.,Hantschel, O.,Young, M.A.,Scheffzek, K.,Veach, D.,Bornmann, W.,Clarkson, B.,Superti-Furga, G.,Kuriyan, J. Structural basis for the autoinhibition of c-Abl tyrosine kinase Cell(Cambridge,Mass.), 112:859-871, 2003 Cited by PubMed: 12654251DOI: 10.1016/S0092-8674(03)00194-6 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.75 Å) |
Structure validation
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