1OO4
P395S mutant of the p85 regulatory subunit of the N-terminal src homology 2 domain of PI3-Kinase complexed to a peptide derived from PDGFr
Summary for 1OO4
| Entry DOI | 10.2210/pdb1oo4/pdb |
| Related | 1OO3 |
| Descriptor | Phosphatidylinositol 3-kinase regulatory alpha subunit, 8-mer peptide from PDGFr (2 entities in total) |
| Functional Keywords | src homology 2 domain p85 regulatory subunit mutant, pdgfr complex, protein binding |
| Biological source | Bos taurus (cattle) More |
| Total number of polymer chains | 2 |
| Total formula weight | 13863.41 |
| Authors | Guenther, U.L.,Weyrauch, B.,Schaffhausen, B. (deposition date: 2003-03-03, release date: 2003-03-25, Last modification date: 2023-11-15) |
| Primary citation | Guenther, U.L.,Weyrauch, B.,Zhang, X.,Schaffhausen, B. Nuclear magnetic resonance structure of the P395S mutant of the N-SH2 domain of the p85 subunit of PI3 kinase: an SH2 domain with altered specificity Biochemistry, 42:11120-11127, 2003 Cited by PubMed: 14503862DOI: 10.1021/bi034353x PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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