1O9S

Crystal structure of a ternary complex of the human histone methyltransferase SET7/9

Summary for 1O9S

• Entry DOI: 10.2210/pdb1o9s/pdb
• Related: 1H3I
• Descriptor: HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-4 SPECIFIC, GENE FRAGMENT FOR HISTONE H3, S-ADENOSYL-L-HOMOCYSTEINE, ... (4 entities in total)
• Functional Keywords: methylation, histone h3, methyltransferase, transferase
• Biological source: HOMO SAPIENS (HUMAN); More
• Cellular location: Nucleus: Q8WTS6
• Total number of polymer chains: 4
• Total formula weight: 61071.98

Authors

Xiao, B.,Jing, C.,Wilson, J.R.,Walker, P.A.,Vasisht, N.,Kelly, G.,Howell, S.,Taylor, I.A.,Blackburn, G.M.,Gamblin, S.J. (deposition date: 2002-12-18, release date: 2003-02-06, Last modification date: 2023-12-13)

• Primary citation: Xiao, B.,Jing, C.,Wilson, J.R.,Walker, P.A.,Vasisht, N.,Kelly, G.,Howell, S.,Taylor, I.A.,Blackburn, G.M.,Gamblin, S.J.; Structure and Catalytic Mechanism of the Human Histone Methyltransferase Set7/9; Nature, 421:652-, 2003; PubMed: 12540855; DOI: 10.1038/NATURE01378

Experimental method

X-RAY DIFFRACTION (1.75 Å)