1O9S
Crystal structure of a ternary complex of the human histone methyltransferase SET7/9
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-4 SPECIFIC | polymer | 259 | 28912.1 | 2 | UniProt (Q8WTS6) Pfam (PF22648) Pfam (PF00856) | HOMO SAPIENS (HUMAN) | HISTONE H3-K4 METHYLTRANSFERASE, H3-K4-HMTASE |
| 2 | C, D (K, L) | GENE FRAGMENT FOR HISTONE H3 | polymer | 10 | 1239.4 | 2 | UniProt (Q16776) UniProt (by SIFTS) (P68431) | HOMO SAPIENS | |
| 3 | E, F (A, B) | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 2 | Chemie (SAH) PubChem (193) PubChem (13792) PubChem (189149) PubChem (439155) PubChem (5284331) PubChem (71170554) PubChem (13231890) PubChem (16760024) PubChem (25210495) PubChem (44361184) PubChem (177678424) PubChem (46936206) PubChem (21125603) PubChem (25203782) PubChem (52224400) PubChem (50989525) PubChem (51380914) PubChem (52224398) PubChem (6419189) PubChem (57544532) PubChem (59046843) PubChem (59170628) PubChem (164157219) PubChem (59576228) PubChem (66805708) PubChem (70689219) PubChem (70702054) PubChem (70832431) PubChem (118374891) PubChem (118560068) PubChem (126969526) PubChem (129105892) PubChem (143518505) PubChem (154578335) PubChem (163054214) PubChem (163335525) | |||
| 4 | G, H, I, J (A, B, K, L) | water | water | 18.0 | 660 | Chemie (HOH) |
Sequence modifications
K, L: 1 - 10 (UniProt: Q16776)
| PDB | External Database | Details |
|---|---|---|
| Tyr 10 | Ser 11 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 60303.2 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 768.8 | |
| All* | Total formula weight | 61072.0 |
