1O27

Crystal structure of Thymidylate Synthase Complementing Protein (TM0449) from Thermotoga maritima with FAD and BrdUMP at 2.3 A resolution

Summary for 1O27

• Entry DOI: 10.2210/pdb1o27/pdb
• Related: 1O24 1O25 1O26 1O28 1O29 1O2A 1O2B
• Descriptor: Thymidylate synthase thyX, 5-BROMO-2'-DEOXYURIDINE-5'-MONOPHOSPHATE, FLAVIN-ADENINE DINUCLEOTIDE, ... (4 entities in total)
• Functional Keywords: tm0449, thymidylate synthase complementing protein, structural genomics, jcsg, joint center for structural genomics, psi, protein structure initiative, transferase
• Biological source: Thermotoga maritima
• Total number of polymer chains: 4
• Total formula weight: 114705.23

Authors

Mathews, I.I.,Deacon, A.M.,Canaves, J.M.,McMullan, D.,Lesley, S.A.,Agarwalla, S.,Kuhn, P.,Joint Center for Structural Genomics (JCSG) (deposition date: 2003-02-18, release date: 2003-06-24, Last modification date: 2023-09-20)

• Primary citation: Mathews, I.I.,Deacon, A.M.,Canaves, J.M.,McMullan, D.,Lesley, S.A.,Agarwalla, S.,Kuhn, P.; Functional Analysis of Substrate and Cofactor Complex Structures of a Thymidylate Synthase-Complementing Protein; Structure, 11:677-690, 2003; PubMed: 12791256; DOI: 10.1016/S0969-2126(03)00097-2

Experimental method

X-RAY DIFFRACTION (2.3 Å)