1O1T

Structure of FPT bound to the CVIM-FPP product

Summary for 1O1T

• Entry DOI: 10.2210/pdb1o1t/pdb
• Related: 1QBQ
• Descriptor: Protein farnesyltransferase alpha subunit, Protein farnesyltransferase beta subunit, MAGNESIUM ION, ... (6 entities in total)
• Functional Keywords: transferase, prenyltransferase
• Biological source: Rattus norvegicus (Norway rat); More
• Total number of polymer chains: 2
• Total formula weight: 92918.44

Authors

Turek-Etienne, T.C.,Strickland, C.L.,Distefano, M.D. (deposition date: 2003-01-14, release date: 2003-05-06, Last modification date: 2024-03-13)

• Primary citation: Turek-Etienne, T.C.,Strickland, C.L.,Distefano, M.D.; Biochemical and Structural Studies with Prenyl Diphosphate Analogues Provide Insights into Isoprenoid Recognition by Protein Farnesyl Transferase; Biochemistry, 42:3716-3724, 2003; PubMed: 12667062; DOI: 10.1021/bi0266838

Experimental method

X-RAY DIFFRACTION (2.1 Å)