1NYU
Crystal Structure of Activin A Bound to the ECD of ActRIIB
Summary for 1NYU
Entry DOI | 10.2210/pdb1nyu/pdb |
Related | 1NYS |
Descriptor | activin receptor, Inhibin beta A chain (2 entities in total) |
Functional Keywords | activin, type ii, tgf beta, actriib, extracellular domain, membrane protein-hormone-growth factor complex, membrane protein/hormone/growth factor |
Biological source | Rattus norvegicus (Norway rat) More |
Cellular location | Cell membrane ; Single-pass type I membrane protein : P38445 Secreted: P08476 |
Total number of polymer chains | 4 |
Total formula weight | 50666.92 |
Authors | Thompson, T.B.,Woodruff, T.K.,Jardetzky, T.S. (deposition date: 2003-02-13, release date: 2003-04-08, Last modification date: 2023-08-16) |
Primary citation | Thompson, T.B.,Woodruff, T.K.,Jardetzky, T.S. Structures of an ActRIIB:activin A complex reveal a novel binding mode for TGF-beta ligand:receptor interactions EMBO J., 22:1555-1566, 2003 Cited by PubMed: 12660162DOI: 10.1093/emboj/cdg156 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.1 Å) |
Structure validation
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