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1NYU

Crystal Structure of Activin A Bound to the ECD of ActRIIB

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, C
(A, C)
activin receptorpolymer10512341.62UniProt (P38445)
Pfam (PF01064)
Rattus norvegicus (Norway rat)
2B, D
(B, D)
Inhibin beta A chainpolymer11612991.92UniProt (P08476)
Pfam (PF00019)
Homo sapiens (human)Activin beta-A chain, Erythroid differentiation protein, EDF
Sequence modifications
A, C: 19 - 119 (UniProt: P38445)
PDBExternal DatabaseDetails
Leu 120-expression tag
Val 121-expression tag
Pro 122-expression tag
Arg 123-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight50666.9
All*Total formula weight50666.9
*Water molecules are not included.

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PDB entries from 2025-06-18

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