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1NYU

Crystal Structure of Activin A Bound to the ECD of ActRIIB

Functional Information from GO Data
ChainGOidnamespacecontents
A0004675molecular_functiontransmembrane receptor protein serine/threonine kinase activity
A0005524molecular_functionATP binding
A0007178biological_processcell surface receptor protein serine/threonine kinase signaling pathway
A0016020cellular_componentmembrane
B0005576cellular_componentextracellular region
B0008083molecular_functiongrowth factor activity
C0004675molecular_functiontransmembrane receptor protein serine/threonine kinase activity
C0005524molecular_functionATP binding
C0007178biological_processcell surface receptor protein serine/threonine kinase signaling pathway
C0016020cellular_componentmembrane
D0005576cellular_componentextracellular region
D0008083molecular_functiongrowth factor activity
Functional Information from PROSITE/UniProt
site_idPS00250
Number of Residues16
DetailsTGF_BETA_1 TGF-beta family signature. IiaPsgYhanyCeGeC
ChainResidueDetails
BILE29-CYS44

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues4
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255
ChainResidueDetails
AASN42
AASN65
CASN42
CASN65

218853

PDB entries from 2024-04-24

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