1NXK
Crystal structure of staurosporine bound to MAP KAP kinase 2
Summary for 1NXK
Entry DOI | 10.2210/pdb1nxk/pdb |
Descriptor | MAP kinase-activated protein kinase 2, STAUROSPORINE, SULFATE ION, ... (4 entities in total) |
Functional Keywords | protein kinase, mk2, phosphorylation, staurosporine, transferase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 4 |
Total formula weight | 186828.14 |
Authors | Underwood, K.W.,Parris, K.D.,Federico, E.,Mosyak, L.,Czerwinski, R.M.,Shane, T.,Taylor, M.,Svenson, K.,Liu, Y.,Hsiao, C.L.,Wolfrom, S.,Malakian, K.,Telliez, J.B.,Lin, L.L.,Kriz, R.W.,Seehra, J.,Somers, W.S.,Stahl, M.L. (deposition date: 2003-02-10, release date: 2003-10-14, Last modification date: 2011-07-13) |
Primary citation | Underwood, K.W.,Parris, K.D.,Federico, E.,Mosyak, L.,Czerwinski, R.M.,Shane, T.,Taylor, M.,Svenson, K.,Liu, Y.,Hsiao, C.L.,Wolfrom, S.,Maguire, M.,Malakian, K.,Telliez, J.B.,Lin, L.L.,Kriz, R.W.,Seehra, J.,Somers, W.S.,Stahl, M.L. Catalytically active MAP KAP kinase 2 structures in complex with staurosporine and ADP reveal differences with the autoinhibited enzyme Structure, 11:627-636, 2003 Cited by PubMed: 12791252DOI: 10.1016/S0969-2126(03)00092-3 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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