1NUN

Crystal Structure Analysis of the FGF10-FGFR2b Complex

Summary for 1NUN

Entry DOI	10.2210/pdb1nun/pdb
Descriptor	Fibroblast growth factor-10, fibroblast growth factor receptor 2 isoform 2, SULFATE ION, ... (5 entities in total)
Functional Keywords	beta-trefoil fold, immunoglobulin-like domain, hormone-growth factor-membrane protein complex, hormone/growth factor/membrane protein
Biological source	Homo sapiens (human) More
Cellular location	Secreted (Potential): O15520 Cell membrane; Single-pass type I membrane protein. Isoform 14: Secreted. Isoform 19: Secreted: P21802
Total number of polymer chains	2
Total formula weight	44492.87
Authors	Yeh, B.K.,Igarashi, M.,Eliseenkova, A.V.,Plotnikov, A.N.,Sher, I.,Ron, D.,Aaronson, S.A.,Mohammadi, M. (deposition date: 2003-01-31, release date: 2003-02-11, Last modification date: 2011-07-13)
Primary citation	Yeh, B.K.,Igarashi, M.,Eliseenkova, A.V.,Plotnikov, A.N.,Sher, I.,Ron, D.,Aaronson, S.A.,Mohammadi, M. Structural basis by which alternative splicing confers specificity in fibroblast growth factor receptors. Proc.Natl.Acad.Sci.USA, 100:2266-2271, 2003 Cited by PubMed: 12591959 DOI: 10.1073/pnas.0436500100 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.9 Å)

Structure validation