1NUN
Crystal Structure Analysis of the FGF10-FGFR2b Complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Fibroblast growth factor-10 | polymer | 145 | 16813.3 | 1 | UniProt (O15520) Pfam (PF00167) | Homo sapiens (human) | FGF-10, keratinocyte growth factor receptor, K-sam protein, protein tyrosine kinase, receptor like 14, FGF receptor, bacteria-expressed kinase, fibroblast growth factor receptor BEK, tyrosylprotein kinase, hydroxyaryl-protein kinase |
| 2 | B (B) | fibroblast growth factor receptor 2 isoform 2 | polymer | 230 | 25957.6 | 1 | UniProt (P21802) Pfam (PF07679) Pfam (PF13927) | Homo sapiens (human) | |
| 3 | C, D (A) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 4 | E (B) | POLYETHYLENE GLYCOL (N=34) | non-polymer | 1529.8 | 1 | Chemie (15P) | |||
| 5 | F, G (A, B) | water | water | 18.0 | 25 | Chemie (HOH) |
Sequence modifications
B: 140 - 369 (UniProt: P21802)
| PDB | External Database | Details |
|---|---|---|
| Mse 162 | Met 162 | modified residue |
| Mse 186 | Met 186 | modified residue |
| Mse 189 | Met 189 | modified residue |
| Mse 218 | Met 218 | modified residue |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 42770.9 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1722.0 | |
| All* | Total formula weight | 44492.9 |
