1NQW

Crystal Structure of Lumazine Synthase from Aquifex aeolicus in Complex with Inhibitor: 5-(6-D-ribitylamino-2,4(1H,3H)pyrimidinedione-5-yl)-1-pentyl-phosphonic acid

1NQW の概要

• エントリーDOI: 10.2210/pdb1nqw/pdb
• 関連するPDBエントリー: 1NQU 1NQV 1NQX
• 分子名称: 6,7-dimethyl-8-ribityllumazine synthase, 5-(6-D-RIBITYLAMINO-2,4(1H,3H)PYRIMIDINEDIONE-5-YL) PENTYL-1-PHOSPHONIC ACID (3 entities in total)
• 機能のキーワード: lumazine synthase, aquifex aeolicus, inhibitor complex, vitamin biosynthesis, catalytic mechanism, transferase
• 由来する生物種: Aquifex aeolicus
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 85692.73

構造登録者

Zhang, X.,Meining, W.,Cushman, M.,Haase, I.,Fischer, M.,Bacher, A.,Ladenstein, R. (登録日: 2003-01-23, 公開日: 2004-01-23, 最終更新日: 2024-02-14)

• 主引用文献: Zhang, X.,Meining, W.,Cushman, M.,Haase, I.,Fischer, M.,Bacher, A.,Ladenstein, R.; A structure-based model of the reaction catalyzed by lumazine synthase from Aquifex aeolicus.; J.Mol.Biol., 328:167-182, 2003; PubMed: 12684006; DOI: 10.1016/S0022-2836(03)00186-4

実験手法

X-RAY DIFFRACTION (2.2 Å)