1NMA

N9 NEURAMINIDASE COMPLEXES WITH ANTIBODIES NC41 AND NC10: EMPIRICAL FREE-ENERGY CALCULATIONS CAPTURE SPECIFICITY TRENDS OBSERVED WITH MUTANT BINDING DATA

Summary for 1NMA

Entry DOI	10.2210/pdb1nma/pdb
Descriptor	N9 NEURAMINIDASE, FAB NC10, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
Functional Keywords	complex (hydrolase-immunoglobulin), complex (hydrolase-immunoglobulin) complex, complex (hydrolase/immunoglobulin)
Biological source	Influenza A virus More
Cellular location	Virion membrane (By similarity): P05803
Total number of polymer chains	3
Total formula weight	70488.68
Authors	Tulip, W.R.,Varghese, J.N.,Colman, P.M. (deposition date: 1994-05-06, release date: 1995-09-15, Last modification date: 2020-07-29)
Primary citation	Tulip, W.R.,Harley, V.R.,Webster, R.G.,Novotny, J. N9 neuraminidase complexes with antibodies NC41 and NC10: empirical free energy calculations capture specificity trends observed with mutant binding data. Biochemistry, 33:7986-7997, 1994 Cited by PubMed: 7517697 DOI: 10.1021/bi00192a002 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3 Å)

Structure validation