1NE7

HUMAN GLUCOSAMINE-6-PHOSPHATE DEAMINASE ISOMERASE AT 1.75 A RESOLUTION COMPLEXED WITH N-ACETYL-GLUCOSAMINE-6-PHOSPHATE AND 2-DEOXY-2-AMINO-GLUCITOL-6-PHOSPHATE

Replaces:  1D9T

Summary for 1NE7

Related1DEA 1HOT 1HOR 1FS5 1FSF 1FS6
DescriptorGlucosamine-6-phosphate isomerase, ALPHA-D-GLUCOSE, N-ACETYL-D-GLUCOSAMINE-6-PHOSPHATE, ... (6 entities in total)
Functional Keywordsv-type like allosteric enzyme, conformational disorder, conformational differences, hydrolase
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm (By similarity) P46926
Total number of polymer chains6
Total molecular weight202483.48
Authors
Arreola, R.,Valderrama, B.,Morante, M.L.,Horjales, E. (deposition date: 2002-12-10, release date: 2003-09-23, Last modification date: 2011-07-13)
Primary citation
Arreola, R.,Valderrama, B.,Morante, M.L.,Horjales, E.
Two mammalian glucosamine-6-phosphate deaminases: a structural and genetic study.
Febs Lett., 551:63-70, 2003
PubMed: 12965206 (PDB entries with the same primary citation)
DOI: 10.1016/S0014-5793(03)00896-2
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.75 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.22570.4%2.6%4.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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