1NDZ

Crystal Structure of Adenosine Deaminase Complexed with FR235999

Summary for 1NDZ

Entry DOI	10.2210/pdb1ndz/pdb
Related	1NDV 1NDW 1NDY
Descriptor	Adenosine Deaminase, ZINC ION, 1-((1R)-1-(HYDROXYMETHYL)-3-(6-((3-(1-METHYL-1H-BENZIMIDAZOL-2-YL)PROPANOYL)AMINO)-1H-INDOL-1-YL)PROPYL)-1H-IMIDAZOLE-4-CARBOXAMIDE, ... (4 entities in total)
Functional Keywords	sbdd, tim-barrel, hydrolase
Biological source	Bos taurus (cattle)
Cellular location	Cell membrane; Peripheral membrane protein; Extracellular side (By similarity): P56658
Total number of polymer chains	1
Total formula weight	40906.64
Authors	Kinoshita, T. (deposition date: 2002-12-09, release date: 2003-12-09, Last modification date: 2024-03-13)
Primary citation	Terasaka, T.,Kinoshita, T.,Kuno, M.,Nakanishi, I. A highly potent non-nucleoside adenosine deaminase inhibitor: efficient drug discovery by intentional lead hybridization J.Am.Chem.Soc., 126:34-35, 2004 Cited by PubMed: 14709046 DOI: 10.1021/ja038606l PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation