1NDZ
Crystal Structure of Adenosine Deaminase Complexed with FR235999
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Adenosine Deaminase | polymer | 356 | 40341.7 | 1 | UniProt (P56658) Pfam (PF00962) | Bos taurus (cattle) | |
| 2 | B (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 3 | C (A) | 1-((1R)-1-(HYDROXYMETHYL)-3-(6-((3-(1-METHYL-1H-BENZIMIDAZOL-2-YL)PROPANOYL)AMINO)-1H-INDOL-1-YL)PROPYL)-1H-IMIDAZOLE-4-CARBOXAMIDE | non-polymer | 499.6 | 1 | Chemie (FR5) | |||
| 4 | D (A) | water | water | 18.0 | 545 | Chemie (HOH) |
Sequence modifications
A: 2 - 357 (UniProt: P56658)
| PDB | External Database | Details |
|---|---|---|
| Asp 8 | Asn 7 | SEE REMARK 999 |
| Lys 32 | Arg 31 | SEE REMARK 999 |
| Arg 33 | Lys 32 | SEE REMARK 999 |
| Thr 57 | Ser 56 | SEE REMARK 999 |
| Asp 60 | Glu 59 | SEE REMARK 999 |
| Asp 77 | Glu 76 | SEE REMARK 999 |
| Ile 79 | Val 78 | SEE REMARK 999 |
| Gln 199 | Lys 198 | SEE REMARK 999 |
| Thr 246 | Ala 245 | SEE REMARK 999 |
| Ile 261 | Val 260 | SEE REMARK 999 |
| Ala 279 | Pro 278 | SEE REMARK 999 |
| Ile 281 | Val 280 | SEE REMARK 999 |
| Lys 313 | Asn 312 | SEE REMARK 999 |
| Asp 314 | Glu 313 | SEE REMARK 999 |
| Arg 352 | Gly 351 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 40341.7 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 565.0 | |
| All* | Total formula weight | 40906.6 |
