1NC3
Crystal structure of E. coli MTA/AdoHcy nucleosidase complexed with formycin A (FMA)
Summary for 1NC3
| Entry DOI | 10.2210/pdb1nc3/pdb |
| Related | 1JYS 1NC1 |
| Descriptor | MTA/SAH nucleosidase, (1S)-1-(7-amino-1H-pyrazolo[4,3-d]pyrimidin-3-yl)-1,4-anhydro-D-ribitol (3 entities in total) |
| Functional Keywords | mixed alpha/beta dimer, hydrolase |
| Biological source | Escherichia coli |
| Total number of polymer chains | 2 |
| Total formula weight | 51510.73 |
| Authors | Lee, J.E.,Cornell, K.A.,Riscoe, M.K.,Howell, P.L. (deposition date: 2002-12-04, release date: 2003-03-25, Last modification date: 2023-08-16) |
| Primary citation | Lee, J.E.,Cornell, K.A.,Riscoe, M.K.,Howell, P.L. Structure of Escherichia coli 5'-methylthioadenosine/ S-adenosylhomocysteine nucleosidase inhibitor complexes provide insight into the conformational changes required for substrate binding and catalysis. J.Biol.Chem., 278:8761-8770, 2003 Cited by PubMed: 12496243DOI: 10.1074/jbc.M210836200 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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