1NC3

Crystal structure of E. coli MTA/AdoHcy nucleosidase complexed with formycin A (FMA)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	MTA/SAH nucleosidase	polymer	242	25488.1	2	UniProt (P24247) Pfam (PF01048) UniProt (by SIFTS) (P0AF12)	Escherichia coli	P46, [Includes: 5'-methylthioadenosine nucleosidase EC 3.2.2.16, ; S-adenosylhomocysteine nucleosidase EC 3.2.2.9, ]
2	C, D (A, B)	(1S)-1-(7-amino-1H-pyrazolo[4,3-d]pyrimidin-3-yl)-1,4-anhydro-D-ribitol	non-polymer		267.2	2	Chemie (FMC)
3	E, F (A, B)	water	water		18.0	200	Chemie (HOH)

Sequence modifications

A, B: 1 - 232 (UniProt: P24247)

PDB	External Database	Details
Phe -9	-	expression tag
Gln -8	-	expression tag
Gly -7	-	expression tag
Ala -6	-	expression tag
Met -5	-	expression tag
Asp -4	-	expression tag
Pro -3	-	expression tag
Glu -2	-	expression tag
Phe -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	50976.2
Non-Polymers*	Number of molecules	2
	Total formula weight	534.5
All*	Total formula weight	51510.7

*Water molecules are not included.