1N4S

Protein Geranylgeranyltransferase type-I Complexed with GGPP and a Geranylgeranylated KKKSKTKCVIL Peptide Product

1N4S の概要

• エントリーDOI: 10.2210/pdb1n4s/pdb
• 関連するPDBエントリー: 1D8D 1DCE 1FPP 1FT1 1KZO 1KZP 1N4P 1N4Q 1N4R 1QBQ
• 分子名称: Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha, Geranylgeranyl transferase type-1 subunit beta, Fusion protein consisting of transforming protein p21b and Ras related protein Rap-2b, ... (8 entities in total)
• 機能のキーワード: protein geranylgeranyltransferase type-i, ggtase, geranylgeranyl, protein prenylation, caax, lipid modification, rap2b, transferase
• 由来する生物種: Rattus norvegicus (Rat); 詳細
• タンパク質・核酸の鎖数: 18
• 化学式量合計: 532131.13

構造登録者

Taylor, J.S.,Reid, T.S.,Casey, P.J.,Beese, L.S. (登録日: 2002-11-01, 公開日: 2003-11-18, 最終更新日: 2017-06-28)

• 主引用文献: Taylor, J.S.,Reid, T.S.,Terry, K.L.,Casey, P.J.,Beese, L.S.; Structure of mammalian protein geranylgeranyltransferase type-I; EMBO J., 22:5963-5974, 2003; PubMed: 14609943; DOI: 10.1093/emboj/cdg571

実験手法

X-RAY DIFFRACTION (2.6 Å)