Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

1N4S

Protein Geranylgeranyltransferase type-I Complexed with GGPP and a Geranylgeranylated KKKSKTKCVIL Peptide Product

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004659	molecular_function	prenyltransferase activity
A	0004660	molecular_function	protein farnesyltransferase activity
A	0004661	molecular_function	protein geranylgeranyltransferase activity
A	0004662	molecular_function	CAAX-protein geranylgeranyltransferase activity
A	0004663	molecular_function	Rab geranylgeranyltransferase activity
A	0005515	molecular_function	protein binding
A	0005737	cellular_component	cytoplasm
A	0005875	cellular_component	microtubule associated complex
A	0005953	cellular_component	CAAX-protein geranylgeranyltransferase complex
A	0005965	cellular_component	protein farnesyltransferase complex
A	0007167	biological_process	enzyme-linked receptor protein signaling pathway
A	0007323	biological_process	peptide pheromone maturation
A	0008017	molecular_function	microtubule binding
A	0008270	molecular_function	zinc ion binding
A	0008284	biological_process	positive regulation of cell population proliferation
A	0008318	molecular_function	protein prenyltransferase activity
A	0014070	biological_process	response to organic cyclic compound
A	0018342	biological_process	protein prenylation
A	0018343	biological_process	protein farnesylation
A	0018344	biological_process	protein geranylgeranylation
A	0030971	molecular_function	receptor tyrosine kinase binding
A	0034097	biological_process	response to cytokine
A	0035022	biological_process	positive regulation of Rac protein signal transduction
A	0036094	molecular_function	small molecule binding
A	0042277	molecular_function	peptide binding
A	0043014	molecular_function	alpha-tubulin binding
A	0043066	biological_process	negative regulation of apoptotic process
A	0045787	biological_process	positive regulation of cell cycle
A	0051770	biological_process	positive regulation of nitric-oxide synthase biosynthetic process
A	0051771	biological_process	negative regulation of nitric-oxide synthase biosynthetic process
A	0060090	molecular_function	molecular adaptor activity
A	0090044	biological_process	positive regulation of tubulin deacetylation
A	1901363	molecular_function	heterocyclic compound binding
A	1904395	biological_process	positive regulation of skeletal muscle acetylcholine-gated channel clustering
B	0003824	molecular_function	catalytic activity
B	0004659	molecular_function	prenyltransferase activity
B	0004661	molecular_function	protein geranylgeranyltransferase activity
B	0004662	molecular_function	CAAX-protein geranylgeranyltransferase activity
B	0005515	molecular_function	protein binding
B	0005953	cellular_component	CAAX-protein geranylgeranyltransferase complex
B	0008270	molecular_function	zinc ion binding
B	0008284	biological_process	positive regulation of cell population proliferation
B	0008318	molecular_function	protein prenyltransferase activity
B	0018344	biological_process	protein geranylgeranylation
B	0034097	biological_process	response to cytokine
B	0036094	molecular_function	small molecule binding
B	0042277	molecular_function	peptide binding
B	0045787	biological_process	positive regulation of cell cycle
B	0046872	molecular_function	metal ion binding
B	0051771	biological_process	negative regulation of nitric-oxide synthase biosynthetic process
B	1901363	molecular_function	heterocyclic compound binding
C	0004659	molecular_function	prenyltransferase activity
C	0004660	molecular_function	protein farnesyltransferase activity
C	0004661	molecular_function	protein geranylgeranyltransferase activity
C	0004662	molecular_function	CAAX-protein geranylgeranyltransferase activity
C	0004663	molecular_function	Rab geranylgeranyltransferase activity
C	0005515	molecular_function	protein binding
C	0005737	cellular_component	cytoplasm
C	0005875	cellular_component	microtubule associated complex
C	0005953	cellular_component	CAAX-protein geranylgeranyltransferase complex
C	0005965	cellular_component	protein farnesyltransferase complex
C	0007167	biological_process	enzyme-linked receptor protein signaling pathway
C	0007323	biological_process	peptide pheromone maturation
C	0008017	molecular_function	microtubule binding
C	0008270	molecular_function	zinc ion binding
C	0008284	biological_process	positive regulation of cell population proliferation
C	0008318	molecular_function	protein prenyltransferase activity
C	0014070	biological_process	response to organic cyclic compound
C	0018342	biological_process	protein prenylation
C	0018343	biological_process	protein farnesylation
C	0018344	biological_process	protein geranylgeranylation
C	0030971	molecular_function	receptor tyrosine kinase binding
C	0034097	biological_process	response to cytokine
C	0035022	biological_process	positive regulation of Rac protein signal transduction
C	0036094	molecular_function	small molecule binding
C	0042277	molecular_function	peptide binding
C	0043014	molecular_function	alpha-tubulin binding
C	0043066	biological_process	negative regulation of apoptotic process
C	0045787	biological_process	positive regulation of cell cycle
C	0051770	biological_process	positive regulation of nitric-oxide synthase biosynthetic process
C	0051771	biological_process	negative regulation of nitric-oxide synthase biosynthetic process
C	0060090	molecular_function	molecular adaptor activity
C	0090044	biological_process	positive regulation of tubulin deacetylation
C	1901363	molecular_function	heterocyclic compound binding
C	1904395	biological_process	positive regulation of skeletal muscle acetylcholine-gated channel clustering
D	0003824	molecular_function	catalytic activity
D	0004659	molecular_function	prenyltransferase activity
D	0004661	molecular_function	protein geranylgeranyltransferase activity
D	0004662	molecular_function	CAAX-protein geranylgeranyltransferase activity
D	0005515	molecular_function	protein binding
D	0005953	cellular_component	CAAX-protein geranylgeranyltransferase complex
D	0008270	molecular_function	zinc ion binding
D	0008284	biological_process	positive regulation of cell population proliferation
D	0008318	molecular_function	protein prenyltransferase activity
D	0018344	biological_process	protein geranylgeranylation
D	0034097	biological_process	response to cytokine
D	0036094	molecular_function	small molecule binding
D	0042277	molecular_function	peptide binding
D	0045787	biological_process	positive regulation of cell cycle
D	0046872	molecular_function	metal ion binding
D	0051771	biological_process	negative regulation of nitric-oxide synthase biosynthetic process
D	1901363	molecular_function	heterocyclic compound binding
E	0004659	molecular_function	prenyltransferase activity
E	0004660	molecular_function	protein farnesyltransferase activity
E	0004661	molecular_function	protein geranylgeranyltransferase activity
E	0004662	molecular_function	CAAX-protein geranylgeranyltransferase activity
E	0004663	molecular_function	Rab geranylgeranyltransferase activity
E	0005515	molecular_function	protein binding
E	0005737	cellular_component	cytoplasm
E	0005875	cellular_component	microtubule associated complex
E	0005953	cellular_component	CAAX-protein geranylgeranyltransferase complex
E	0005965	cellular_component	protein farnesyltransferase complex
E	0007167	biological_process	enzyme-linked receptor protein signaling pathway
E	0007323	biological_process	peptide pheromone maturation
E	0008017	molecular_function	microtubule binding
E	0008270	molecular_function	zinc ion binding
E	0008284	biological_process	positive regulation of cell population proliferation
E	0008318	molecular_function	protein prenyltransferase activity
E	0014070	biological_process	response to organic cyclic compound
E	0018342	biological_process	protein prenylation
E	0018343	biological_process	protein farnesylation
E	0018344	biological_process	protein geranylgeranylation
E	0030971	molecular_function	receptor tyrosine kinase binding
E	0034097	biological_process	response to cytokine
E	0035022	biological_process	positive regulation of Rac protein signal transduction
E	0036094	molecular_function	small molecule binding
E	0042277	molecular_function	peptide binding
E	0043014	molecular_function	alpha-tubulin binding
E	0043066	biological_process	negative regulation of apoptotic process
E	0045787	biological_process	positive regulation of cell cycle
E	0051770	biological_process	positive regulation of nitric-oxide synthase biosynthetic process
E	0051771	biological_process	negative regulation of nitric-oxide synthase biosynthetic process
E	0060090	molecular_function	molecular adaptor activity
E	0090044	biological_process	positive regulation of tubulin deacetylation
E	1901363	molecular_function	heterocyclic compound binding
E	1904395	biological_process	positive regulation of skeletal muscle acetylcholine-gated channel clustering
F	0003824	molecular_function	catalytic activity
F	0004659	molecular_function	prenyltransferase activity
F	0004661	molecular_function	protein geranylgeranyltransferase activity
F	0004662	molecular_function	CAAX-protein geranylgeranyltransferase activity
F	0005515	molecular_function	protein binding
F	0005953	cellular_component	CAAX-protein geranylgeranyltransferase complex
F	0008270	molecular_function	zinc ion binding
F	0008284	biological_process	positive regulation of cell population proliferation
F	0008318	molecular_function	protein prenyltransferase activity
F	0018344	biological_process	protein geranylgeranylation
F	0034097	biological_process	response to cytokine
F	0036094	molecular_function	small molecule binding
F	0042277	molecular_function	peptide binding
F	0045787	biological_process	positive regulation of cell cycle
F	0046872	molecular_function	metal ion binding
F	0051771	biological_process	negative regulation of nitric-oxide synthase biosynthetic process
F	1901363	molecular_function	heterocyclic compound binding
G	0004659	molecular_function	prenyltransferase activity
G	0004660	molecular_function	protein farnesyltransferase activity
G	0004661	molecular_function	protein geranylgeranyltransferase activity
G	0004662	molecular_function	CAAX-protein geranylgeranyltransferase activity
G	0004663	molecular_function	Rab geranylgeranyltransferase activity
G	0005515	molecular_function	protein binding
G	0005737	cellular_component	cytoplasm
G	0005875	cellular_component	microtubule associated complex
G	0005953	cellular_component	CAAX-protein geranylgeranyltransferase complex
G	0005965	cellular_component	protein farnesyltransferase complex
G	0007167	biological_process	enzyme-linked receptor protein signaling pathway
G	0007323	biological_process	peptide pheromone maturation
G	0008017	molecular_function	microtubule binding
G	0008270	molecular_function	zinc ion binding
G	0008284	biological_process	positive regulation of cell population proliferation
G	0008318	molecular_function	protein prenyltransferase activity
G	0014070	biological_process	response to organic cyclic compound
G	0018342	biological_process	protein prenylation
G	0018343	biological_process	protein farnesylation
G	0018344	biological_process	protein geranylgeranylation
G	0030971	molecular_function	receptor tyrosine kinase binding
G	0034097	biological_process	response to cytokine
G	0035022	biological_process	positive regulation of Rac protein signal transduction
G	0036094	molecular_function	small molecule binding
G	0042277	molecular_function	peptide binding
G	0043014	molecular_function	alpha-tubulin binding
G	0043066	biological_process	negative regulation of apoptotic process
G	0045787	biological_process	positive regulation of cell cycle
G	0051770	biological_process	positive regulation of nitric-oxide synthase biosynthetic process
G	0051771	biological_process	negative regulation of nitric-oxide synthase biosynthetic process
G	0060090	molecular_function	molecular adaptor activity
G	0090044	biological_process	positive regulation of tubulin deacetylation
G	1901363	molecular_function	heterocyclic compound binding
G	1904395	biological_process	positive regulation of skeletal muscle acetylcholine-gated channel clustering
H	0003824	molecular_function	catalytic activity
H	0004659	molecular_function	prenyltransferase activity
H	0004661	molecular_function	protein geranylgeranyltransferase activity
H	0004662	molecular_function	CAAX-protein geranylgeranyltransferase activity
H	0005515	molecular_function	protein binding
H	0005953	cellular_component	CAAX-protein geranylgeranyltransferase complex
H	0008270	molecular_function	zinc ion binding
H	0008284	biological_process	positive regulation of cell population proliferation
H	0008318	molecular_function	protein prenyltransferase activity
H	0018344	biological_process	protein geranylgeranylation
H	0034097	biological_process	response to cytokine
H	0036094	molecular_function	small molecule binding
H	0042277	molecular_function	peptide binding
H	0045787	biological_process	positive regulation of cell cycle
H	0046872	molecular_function	metal ion binding
H	0051771	biological_process	negative regulation of nitric-oxide synthase biosynthetic process
H	1901363	molecular_function	heterocyclic compound binding
I	0004659	molecular_function	prenyltransferase activity
I	0004660	molecular_function	protein farnesyltransferase activity
I	0004661	molecular_function	protein geranylgeranyltransferase activity
I	0004662	molecular_function	CAAX-protein geranylgeranyltransferase activity
I	0004663	molecular_function	Rab geranylgeranyltransferase activity
I	0005515	molecular_function	protein binding
I	0005737	cellular_component	cytoplasm
I	0005875	cellular_component	microtubule associated complex
I	0005953	cellular_component	CAAX-protein geranylgeranyltransferase complex
I	0005965	cellular_component	protein farnesyltransferase complex
I	0007167	biological_process	enzyme-linked receptor protein signaling pathway
I	0007323	biological_process	peptide pheromone maturation
I	0008017	molecular_function	microtubule binding
I	0008270	molecular_function	zinc ion binding
I	0008284	biological_process	positive regulation of cell population proliferation
I	0008318	molecular_function	protein prenyltransferase activity
I	0014070	biological_process	response to organic cyclic compound
I	0018342	biological_process	protein prenylation
I	0018343	biological_process	protein farnesylation
I	0018344	biological_process	protein geranylgeranylation
I	0030971	molecular_function	receptor tyrosine kinase binding
I	0034097	biological_process	response to cytokine
I	0035022	biological_process	positive regulation of Rac protein signal transduction
I	0036094	molecular_function	small molecule binding
I	0042277	molecular_function	peptide binding
I	0043014	molecular_function	alpha-tubulin binding
I	0043066	biological_process	negative regulation of apoptotic process
I	0045787	biological_process	positive regulation of cell cycle
I	0051770	biological_process	positive regulation of nitric-oxide synthase biosynthetic process
I	0051771	biological_process	negative regulation of nitric-oxide synthase biosynthetic process
I	0060090	molecular_function	molecular adaptor activity
I	0090044	biological_process	positive regulation of tubulin deacetylation
I	1901363	molecular_function	heterocyclic compound binding
I	1904395	biological_process	positive regulation of skeletal muscle acetylcholine-gated channel clustering
J	0003824	molecular_function	catalytic activity
J	0004659	molecular_function	prenyltransferase activity
J	0004661	molecular_function	protein geranylgeranyltransferase activity
J	0004662	molecular_function	CAAX-protein geranylgeranyltransferase activity
J	0005515	molecular_function	protein binding
J	0005953	cellular_component	CAAX-protein geranylgeranyltransferase complex
J	0008270	molecular_function	zinc ion binding
J	0008284	biological_process	positive regulation of cell population proliferation
J	0008318	molecular_function	protein prenyltransferase activity
J	0018344	biological_process	protein geranylgeranylation
J	0034097	biological_process	response to cytokine
J	0036094	molecular_function	small molecule binding
J	0042277	molecular_function	peptide binding
J	0045787	biological_process	positive regulation of cell cycle
J	0046872	molecular_function	metal ion binding
J	0051771	biological_process	negative regulation of nitric-oxide synthase biosynthetic process
J	1901363	molecular_function	heterocyclic compound binding
K	0004659	molecular_function	prenyltransferase activity
K	0004660	molecular_function	protein farnesyltransferase activity
K	0004661	molecular_function	protein geranylgeranyltransferase activity
K	0004662	molecular_function	CAAX-protein geranylgeranyltransferase activity
K	0004663	molecular_function	Rab geranylgeranyltransferase activity
K	0005515	molecular_function	protein binding
K	0005737	cellular_component	cytoplasm
K	0005875	cellular_component	microtubule associated complex
K	0005953	cellular_component	CAAX-protein geranylgeranyltransferase complex
K	0005965	cellular_component	protein farnesyltransferase complex
K	0007167	biological_process	enzyme-linked receptor protein signaling pathway
K	0007323	biological_process	peptide pheromone maturation
K	0008017	molecular_function	microtubule binding
K	0008270	molecular_function	zinc ion binding
K	0008284	biological_process	positive regulation of cell population proliferation
K	0008318	molecular_function	protein prenyltransferase activity
K	0014070	biological_process	response to organic cyclic compound
K	0018342	biological_process	protein prenylation
K	0018343	biological_process	protein farnesylation
K	0018344	biological_process	protein geranylgeranylation
K	0030971	molecular_function	receptor tyrosine kinase binding
K	0034097	biological_process	response to cytokine
K	0035022	biological_process	positive regulation of Rac protein signal transduction
K	0036094	molecular_function	small molecule binding
K	0042277	molecular_function	peptide binding
K	0043014	molecular_function	alpha-tubulin binding
K	0043066	biological_process	negative regulation of apoptotic process
K	0045787	biological_process	positive regulation of cell cycle
K	0051770	biological_process	positive regulation of nitric-oxide synthase biosynthetic process
K	0051771	biological_process	negative regulation of nitric-oxide synthase biosynthetic process
K	0060090	molecular_function	molecular adaptor activity
K	0090044	biological_process	positive regulation of tubulin deacetylation
K	1901363	molecular_function	heterocyclic compound binding
K	1904395	biological_process	positive regulation of skeletal muscle acetylcholine-gated channel clustering
L	0003824	molecular_function	catalytic activity
L	0004659	molecular_function	prenyltransferase activity
L	0004661	molecular_function	protein geranylgeranyltransferase activity
L	0004662	molecular_function	CAAX-protein geranylgeranyltransferase activity
L	0005515	molecular_function	protein binding
L	0005953	cellular_component	CAAX-protein geranylgeranyltransferase complex
L	0008270	molecular_function	zinc ion binding
L	0008284	biological_process	positive regulation of cell population proliferation
L	0008318	molecular_function	protein prenyltransferase activity
L	0018344	biological_process	protein geranylgeranylation
L	0034097	biological_process	response to cytokine
L	0036094	molecular_function	small molecule binding
L	0042277	molecular_function	peptide binding
L	0045787	biological_process	positive regulation of cell cycle
L	0046872	molecular_function	metal ion binding
L	0051771	biological_process	negative regulation of nitric-oxide synthase biosynthetic process
L	1901363	molecular_function	heterocyclic compound binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN B 378

Chain	Residue
B	ASP269
B	CYS271
B	HIS321
B	HOH1559

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN D 378

Chain	Residue
D	ASP269
D	CYS271
D	HIS321
D	HOH1589

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN F 378

Chain	Residue
F	CYS271
F	HIS321
F	HOH1586
F	ASP269

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN H 378

Chain	Residue
H	ASP269
H	CYS271
H	HIS321
H	HOH1560

site_id	AC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN J 378

Chain	Residue
J	ASP269
J	CYS271
J	HIS321
J	HOH1581

site_id	AC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN L 378

Chain	Residue
L	ASP269
L	CYS271
L	HIS321
L	HOH1630

site_id	AC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL B 1401

Chain	Residue
B	LYS284
B	ILE285
B	PHE286
B	GLN287

site_id	AC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL C 1402

Chain	Residue
C	ARG287
C	ARG291
C	TYR292

site_id	AC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL D 1403

Chain	Residue
D	LYS284
D	ILE285
D	PHE286
D	GLN287

site_id	BC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL F 1404

Chain	Residue
F	LYS284
F	PHE286
F	GLN287

site_id	BC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL G 1405

Chain	Residue
G	ARG287
G	TYR292
G	HOH1411

site_id	BC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL H 1406

Chain	Residue
H	LYS284
H	ILE285
H	PHE286
H	GLN287

site_id	BC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL J 1407

Chain	Residue
J	LYS284
J	ILE285
J	PHE286
J	GLN287

site_id	BC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CL K 1408

Chain	Residue
A	HOH408
K	ARG287
K	TYR292
K	HOH1417
K	HOH1477

site_id	BC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL L 1409

Chain	Residue
L	LYS284
L	ILE285
L	PHE286
L	GLN287

site_id	BC7
Number of Residues	9
Details	BINDING SITE FOR RESIDUE GER M 1108

Chain	Residue
B	TYR40
B	ILE50
B	PHE53
B	PRO317
B	ASP318
B	ALA319
M	CYS108
M	VAL109
M	ILE110

site_id	BC8
Number of Residues	8
Details	BINDING SITE FOR RESIDUE GER N 1208

Chain	Residue
D	TYR40
D	ILE50
D	PHE53
D	ASP318
D	ALA319
N	CYS208
N	VAL209
N	ILE210

site_id	BC9
Number of Residues	8
Details	BINDING SITE FOR RESIDUE GER O 1308

Chain	Residue
F	ILE50
F	PHE53
F	PRO317
F	ASP318
F	ALA319
O	CYS308
O	VAL309
O	ILE310

site_id	CC1
Number of Residues	8
Details	BINDING SITE FOR RESIDUE GER P 1408

Chain	Residue
H	TYR40
H	ILE50
H	PHE53
H	ASP318
H	ALA319
P	CYS408
P	VAL409
P	ILE410

site_id	CC2
Number of Residues	9
Details	BINDING SITE FOR RESIDUE GER Q 1508

Chain	Residue
Q	ILE510
J	TYR40
J	ILE50
J	PHE53
J	PRO317
J	ASP318
J	ALA319
Q	CYS508
Q	VAL509

site_id	CC3
Number of Residues	8
Details	BINDING SITE FOR RESIDUE GER R 1608

Chain	Residue
L	TYR40
L	ILE50
L	PHE53
L	ASP318
L	ALA319
R	CYS608
R	VAL609
R	ILE610

site_id	CC4
Number of Residues	13
Details	BINDING SITE FOR RESIDUE GRG B 1501

Chain	Residue
A	TYR200
B	ARG173
B	GLN212
B	HIS219
B	GLY221
B	ARG263
B	LYS266
B	TYR272
B	TRP275
B	ASN345
B	HOH1529
B	HOH1542
B	HOH1543

site_id	CC5
Number of Residues	14
Details	BINDING SITE FOR RESIDUE GRG D 1502

Chain	Residue
C	TYR200
C	HOH1478
D	ARG173
D	GLN212
D	HIS219
D	GLY221
D	ARG263
D	LYS266
D	TYR272
D	TRP275
D	ASN345
D	HOH1544
D	HOH1562
D	HOH1610

site_id	CC6
Number of Residues	13
Details	BINDING SITE FOR RESIDUE GRG F 1503

Chain	Residue
E	TYR200
F	ARG173
F	GLN212
F	HIS219
F	GLY221
F	ARG263
F	LYS266
F	TYR272
F	TRP275
F	ASN345
F	HOH1543
F	HOH1558
F	HOH1596

site_id	CC7
Number of Residues	14
Details	BINDING SITE FOR RESIDUE GRG H 1504

Chain	Residue
G	TYR200
H	PHE53
H	ARG173
H	GLN212
H	HIS219
H	GLY221
H	ARG263
H	LYS266
H	TYR272
H	TRP275
H	ASN345
H	HOH1525
H	HOH1528
H	HOH1550

site_id	CC8
Number of Residues	14
Details	BINDING SITE FOR RESIDUE GRG J 1505

Chain	Residue
I	TYR200
I	HOH475
J	ARG173
J	HIS219
J	GLY221
J	ARG263
J	LYS266
J	TYR272
J	TRP275
J	ASN345
J	HOH1514
J	HOH1545
J	HOH1548
J	HOH1556

site_id	CC9
Number of Residues	13
Details	BINDING SITE FOR RESIDUE GRG L 1506

Chain	Residue
K	TYR200
L	ARG173
L	HIS219
L	GLY221
L	ARG263
L	LYS266
L	TYR272
L	TRP275
L	HOH1515
L	HOH1564
L	HOH1579
L	HOH1594
L	HOH1631

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	MOD_RES: Cysteine methyl ester => ECO:0000269\|PubMed:27791178, ECO:0007744\|PDB:5TAR, ECO:0007744\|PDB:5TB5

Chain	Residue	Details
M	CYS108
D	CYS271
D	TYR272
D	HIS321
F	HIS219
F	ARG263
F	ASP269
F	CYS271
F	TYR272
F	HIS321
H	HIS219
N	CYS208
H	ARG263
H	ASP269
H	CYS271
H	TYR272
H	HIS321
J	HIS219
J	ARG263
J	ASP269
J	CYS271
J	TYR272
O	CYS308
J	HIS321
L	HIS219
L	ARG263
L	ASP269
L	CYS271
L	TYR272
L	HIS321
P	CYS408
Q	CYS508
R	CYS608
D	HIS219
D	ARG263
D	ASP269

site_id	SWS_FT_FI2
Number of Residues	6
Details	LIPID: N6-palmitoyl lysine => ECO:0000305\|PubMed:29239724

Chain	Residue	Details
M	LYS107
N	LYS207
O	LYS307
P	LYS407
Q	LYS507
R	LYS607

site_id	SWS_FT_FI3
Number of Residues	6
Details	LIPID: S-farnesyl cysteine => ECO:0000269\|PubMed:27791178, ECO:0000305\|PubMed:24415755, ECO:0007744\|PDB:5TAR, ECO:0007744\|PDB:5TB5

Chain	Residue	Details
M	CYS108
N	CYS208
O	CYS308
P	CYS408
Q	CYS508
R	CYS608

Catalytic Information from CSA

site_id	CSA1
Number of Residues	2
Details	Annotated By Reference To The Literature 1d8d

Chain	Residue	Details
A	LYS164
B	TYR272

site_id	CSA2
Number of Residues	2
Details	Annotated By Reference To The Literature 1d8d

Chain	Residue	Details
C	LYS164
D	TYR272

site_id	CSA3
Number of Residues	2
Details	Annotated By Reference To The Literature 1d8d

Chain	Residue	Details
F	TYR272
E	LYS164

site_id	CSA4
Number of Residues	2
Details	Annotated By Reference To The Literature 1d8d

Chain	Residue	Details
H	TYR272
G	LYS164

site_id	CSA5
Number of Residues	2
Details	Annotated By Reference To The Literature 1d8d

Chain	Residue	Details
J	TYR272
I	LYS164

site_id	CSA6
Number of Residues	2
Details	Annotated By Reference To The Literature 1d8d

Chain	Residue	Details
K	LYS164
L	TYR272

site_id	MCSA1
Number of Residues	1
Details	M-CSA 484

Chain	Residue	Details
A	LYS164	electrostatic stabiliser

site_id	MCSA2
Number of Residues	1
Details	M-CSA 484

Chain	Residue	Details
C	LYS164	electrostatic stabiliser

site_id	MCSA3
Number of Residues	1
Details	M-CSA 484

Chain	Residue	Details
E	LYS164	electrostatic stabiliser

site_id	MCSA4
Number of Residues	1
Details	M-CSA 484

Chain	Residue	Details
G	LYS164	electrostatic stabiliser

site_id	MCSA5
Number of Residues	1
Details	M-CSA 484

Chain	Residue	Details
I	LYS164	electrostatic stabiliser

site_id	MCSA6
Number of Residues	1
Details	M-CSA 484

Chain	Residue	Details
K	LYS164	electrostatic stabiliser

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)