1MY5

NF-kappaB p65 subunit dimerization domain homodimer

Summary for 1MY5

Entry DOI	10.2210/pdb1my5/pdb
Related	1bft 1my7
Descriptor	NF-kappaB p65 (RelA) subunit (2 entities in total)
Functional Keywords	immunoglobulin, ig, beta-sandwich, beta-sheet, homodimer, dna-binding, transcription regulation, activator, nuclear protein, phosphorylation, transcription
Biological source	Mus musculus (house mouse)
Cellular location	Nucleus: Q04207
Total number of polymer chains	2
Total formula weight	26403.76
Authors	Huxford, T.,Mishler, D.,Phelps, C.B.,Huang, D.-B.,Sengchanthalangsy, L.L.,Reeves, R.,Hughes, C.A.,Komives, E.A.,Ghosh, G. (deposition date: 2002-10-03, release date: 2002-12-04, Last modification date: 2024-02-14)
Primary citation	Huxford, T.,Mishler, D.,Phelps, C.B.,Huang, D.-B.,Sengchanthalangsy, L.L.,Reeves, R.,Hughes, C.A.,Komives, E.A.,Ghosh, G. Solvent exposed non-contacting amino acids play a critical role in NF-kappaB/I kappaB alpha complex formation J.Mol.Biol., 324:587-597, 2002 Cited by PubMed: 12460563 DOI: 10.1016/S0022-2836(02)01149-X PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation