1MT9
Viability of a drug-resistant HIV-1 protease mutant: structural insights for better antiviral therapy
Summary for 1MT9
Entry DOI | 10.2210/pdb1mt9/pdb |
Related | 1KJ4 1MT7 1MT8 1MTB 1MTR |
Descriptor | PROTEASE RETROPEPSIN, p1-p6 Gag substrate decapeptide, PHOSPHATE ION, ... (4 entities in total) |
Functional Keywords | matrix, capsid, gag cleavage, drug resistance, substrate recognition, hydrolase, hydrolase-hydrolase substrate complex, hydrolase/hydrolase substrate |
Biological source | Human immunodeficiency virus 1 More |
Cellular location | Gag-Pol polyprotein: Host cell membrane; Lipid-anchor. Matrix protein p17: Virion membrane; Lipid- anchor . Capsid protein p24: Virion . Nucleocapsid protein p7: Virion . Reverse transcriptase/ribonuclease H: Virion . Integrase: Virion : P03369 |
Total number of polymer chains | 3 |
Total formula weight | 23288.60 |
Authors | Prabu-Jeyabalan, M.,Nalivaika, E.A.,King, N.M.,Schiffer, C.A. (deposition date: 2002-09-20, release date: 2003-01-07, Last modification date: 2024-02-14) |
Primary citation | Prabu-Jeyabalan, M.,Nalivaika, E.A.,King, N.M.,Schiffer, C.A. Viability of drug-resistant human immunodeficiency virus type 1 protease variant: structural insights for better antiviral therapy J.Virol., 77:1305-1315, 2003 Cited by PubMed: 12502847DOI: 10.1128/JVI.77.2.1306-1315.2003 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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