1MFI
CRYSTAL STRUCTURE OF MACROPHAGE MIGRATION INHIBITORY FACTOR COMPLEXED WITH (E)-2-FLUORO-P-HYDROXYCINNAMATE
Summary for 1MFI
Entry DOI | 10.2210/pdb1mfi/pdb |
Descriptor | PROTEIN (MACROPHAGE MIGRATION INHIBITORY FACTOR), 2-FLUORO-3-(4-HYDROXYPHENYL)-2E-PROPENEOATE (3 entities in total) |
Functional Keywords | cytokine, macrophage, inflammatory response, tautomerase, viral protein |
Biological source | Mus musculus (house mouse) |
Cellular location | Secreted : P34884 |
Total number of polymer chains | 3 |
Total formula weight | 37692.50 |
Authors | Taylor, A.B.,Johnson Jr., W.H.,Czerwinski, R.M.,Whitman, C.P.,Hackert, M.L. (deposition date: 1998-08-12, release date: 1999-06-22, Last modification date: 2024-04-03) |
Primary citation | Taylor, A.B.,Johnson Jr., W.H.,Czerwinski, R.M.,Li, H.S.,Hackert, M.L.,Whitman, C.P. Crystal structure of macrophage migration inhibitory factor complexed with (E)-2-fluoro-p-hydroxycinnamate at 1.8 A resolution: implications for enzymatic catalysis and inhibition. Biochemistry, 38:7444-7452, 1999 Cited by PubMed: 10360941DOI: 10.1021/bi9904048 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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