1ME6

CRYSTAL STRUCTURE OF PLASMEPSIN II, AN ASPARTYL PROTEASE FROM PLASMODIUM FALCIPARUM, IN COMPLEX WITH A STATINE-BASED INHIBITOR

Summary for 1ME6

• Entry DOI: 10.2210/pdb1me6/pdb
• Related: 1QS8 1SME
• Descriptor: Plasmepsin II, 3-HYDROXY-6-METHYL-4-(3-METHYL-2-(3-METHYL-2-(3-METHYL-BUTYRYLAMINO)-BUTYRYLAMINO)-BUTYRYLAMINO)-HEPTANOIC ACID ETHYL ESTER (3 entities in total)
• Functional Keywords: protein-ligand complex, hydrolase
• Biological source: Plasmodium falciparum (malaria parasite P. falciparum)
• Cellular location: Vacuole: P46925
• Total number of polymer chains: 2
• Total formula weight: 74878.78

Authors

Freire, E.,Nezami, A.G.,Amzel, L.M. (deposition date: 2002-08-08, release date: 2004-01-20, Last modification date: 2017-10-11)

• Primary citation: Freire, E.,Nezami, A.G.,Amzel, L.M.; CRYSTAL STRUCTURE OF PLASMEPSIN II, AN ASPARTYL PROTEASE FROM PLASMODIUM FALCIPARUM, IN COMPLEX WITH A STATINE-BASED INHIBITOR; TO BE PUBLISHED,

Experimental method

X-RAY DIFFRACTION (2.7 Å)